Allegra 24-Hour vs. 12-Hour Showdown: Tested for Seasonal Relief When the pollen count spikes and your nose feels like it's been dipped in a sopping wet towel, the battle between Allegra's 24-hour and 12-hour formulations becomes a critical one. Both options are powered by the same trusted antihistamine, fexofenadine HCI (180 mg vs. 60 mg), but their performance diverges like a fork in the road. The 24-Hour version, with its 180 mg dose, acts as a fortress against symptoms-blocking histamines for a full day and night without drowsy side effects. It's ideal for those who need unwavering relief during long stretches of high allergen activity, like a weekend getaway or a busy work week. However, its 100-count pack (with a handy bonus tissue pack) is a balm for budget-conscious buyers, while the 45-count variant leans more toward portability and single-dose convenience. In contrast, the 12-Hour tablets offer a more measured approach, with 60 mg of fexofenadine providing relief for half the duration. This version suits individuals who prefer to manage symptoms in smaller, more flexible increments-or who are sensitive to higher doses. Its 24-count packaging ensures you're never caught without a few pills, though it may require more frequent trips to the medicine cabinet. So, which reigns supreme? The 24-hour formula wins for stamina, while the 12-hour version triumphs in adaptability. Your choice depends on the relentless rhythm of your allergy season-and whether you're building a fortress or a safety net.